DNA REPLICATION & REPAIR GROUP
Selected publications

Publications

Selected publications

Representative and landmark publications from the group and closely related collaborative work. For a comprehensive list please consult institutional and PubMed records.
2005

Nature

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

2005

Cell Cycle

Poly(ADP-ribose) polymerase (PARP-1) in homologous recombination and as a target for cancer therapy

2009

The EMBO Journal

PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination

2017

DNA Repair

Specific killing of DNA damage-response deficient cells with inhibitors of poly(ADP-ribose) glycohydrolase

2020

Frontiers in Molecular Biosciences

Poly(ADP-Ribose) Glycohydrolase (PARG) vs. Poly(ADP-Ribose) Polymerase (PARP): function in genome maintenance and relevance of inhibitors for anti-cancer therapy

2021

Cancers

Increased Replication Stress Determines ATR Inhibitor Sensitivity in Neuroblastoma Cells

2024

Journal of Medicinal Chemistry

Photostable Iridium(III) Cyclometallated Complex is an Efficient Photosensitizer for Killing Multiple Cancer Cell Lines and 3D Models under Low Doses of Visible Light